Goku vs. Superman
One of my favourite game systems from the last few years is the DC UNIVERSE MINIATURE GAME from Knight Models. It's a "beer & pretzels" tabletop game about superheroes duking it out with big punches and laser beams. But the reason I really like it, is that the system itself is flexible enough to write a lot of homebrew or house-rules. For example, bringing anime characters in to fight the Western superheroes.